Know about uric acid, other than the 3-highs, the 4th health indicator you should not ignore

Lots of people receive their physical check-up results and start to be nervous when seeing the warning about uric acid level. What will high uric acid affect the body? And what is the cause of high uric acid? Mr. Taizaku here will be introducing to you the knowledge about uric acid, walking you through this important health indicator we should not ignore.


What is uric acid? And how is it produced?

Uric acid is produced by the breakdown of amino acid and nucleic acid within our body, or by the breakdown of purine contained in the food we eat. Generally, 80% of the uric acid is produced by the metabolism within our body, and the other 20% is from the food. The amount of uric acid produced in 1 day is about 750 mg, and 500 mg of all can be transferred by the kidney and taken out of the body through urine.


What is the standard value of uric acid?

Because only about 500 mg can be taken out of the body in 1 day, the rest of the uric acid will be in our blood. Normally, there should be 7 mg in every 100 mg blood for male, and 6 mg for female. That’s the normal value of the uric acid level.

However, the research has found, because female hormones can help improve the uric acid excretion, so the gout symptoms on male to female is 9:1. Females will need to pay more attention on the high uric acid problem after menopause, that they gradually lose the protection of female hormones.


The 2 types of high uric acid, and what are the causes

As for why the uric acid exceeds the standard? It’s simply just, 1. The uric acid metabolic rate is lower than normal, or 2. The body produces too much uric acid. These 2 types have different causes:


The causes of low uric acid metabolic rate

The main organ that deals with uric acid metabolism is the kidney. If the kidney is dysfunctional, or genetically the body lacks the HGPRT enzyme which is also for uric acid metabolism, will lead to uric acid metabolism dysfunction, and uric acid accumulates, even form crystals in the kidney, which will damage the kidney, affecting its metabolism, and makes the high uric acid condition worse and worse. This is absolutely a vicious circle!


Furthermore, alcohol can push the liver to produce more uric acid, and at the same time the lactate that is produced after metabolism is also affecting the uric acid metabolic rate. Besides alcohol, taking too many sweets may also cause a metabolic disorder, and make the uric acid can’t be taken out of the body easily. Sugary foods and beverages should be avoided in case of the rise of uric acid.


The causes of producing too much uric acid by the body

The body takes too much food that contain purine producing too much uric acid, then the uric acid metabolism is not faster enough than it is produced, and common high purine foods are in 4 types:


  1. Animal meats
    Such as beef, pork, chicken, and red meat contains even more purine.


  1. Animal offals
    Such as the heart, liver, intestine of pig, cattle, chicken.


  1. Sea foods
    Such as sardine fish, Anchovy fish, tuna, oyster, crab, lobster, octopus, etc.

Root and stem vegetables
Such as dry mushroom, natto


The mix of both types above

The mix type is while the body is in low uric acid metabolism and produces too much uric acid at the same time. To improve this condition needs to boost the uric acid metabolism and decrease the production of uric acid.


What diseases will high uric acid cause? 7 common complications to pay attention to

If the uric acid is higher than 7.0 mg/dL, this condition is called hyperuricemia. It’s easy to develop gout under this condition. Hyperuricemia also can cause some complications as listed below:

1. Gouty arthritis


Gouty arthritis is because uric acid crystals build up in the joint, and it causes inflammation, swelling, and pain.


2. Gout stones (Uric acid stones)

Due to too much the uric acid crystallization in the joint and deforms the joint causing the pain.

3. Stroke


When uric acid crystals build up in the blood vessel, it causes atherosclerosis, leading to a high blood pressure condition, and it results in a stroke.


4. Ischemic heart disease


When uric acid crystals build up in the heart, it blocks the coronary artery and results in ischemic heart disease.


5. Kidney dysfunction


Uric acid stones stacking in the kidney damages the kidney and affects the metabolism.


6. Uremia


When the kidney is damaged, the metabolism gets poor, so the toxic substances stay in the body and only will be found while doing the urine check-up.


7. Urethral stones


When the uric acid crystals accumulate in between the ureter, bladder, urethra, it may block the urine path, and sometimes it may cause hematuria (blood in urine). 



Notes: The higher the uric acid goes, the higher possibility other complications may happen. So some medical professionals are proposing to include “high uric acid” into the so-called “3-highs” (high blood pressure, high blood glucose, high blood lipid) as the 4th-high.


How to lower the uric acid? See a professional doctor and do uric acid check-up, and improve the rise of uric acid

The symptom of hyperuricemia usually has 2 phases, chronic phase and acute phase. During the chronic phase, it is suggested that you can go to a hospital seeking professional doctors’ help. Through some physical  check-ups on the health indicators like weight, blood pressure, blood glucose, triglycerides, creatinine, and find out the reason that causes the hyperuricemia. And plus regular blood check-up, lifestyle adjustment, diet habit improvement.


Ways to lower uric acid when gouty arthritis happens

If acute gouty arthritis happens, you need medication treatment to stop the pain and lower the uric acid in the body. 3 common medicines below:

1. Non-Steroidal Anti-Inflammatory Drug (NSAID)

It sometimes is used as primary medicine treating acute gout attack, but if you recently have had peptic ulcer disease, acute insufficient cardiaque, kidney dysfunction, you are not suggested to take this kind of medicine. And for consistent use, it may cause damage to the kidney.

2. Corticosteroid

If you can not use NSAID, then corticosteroid can be taken to ease the gouty pain. But steroids may have side effects like the rise of blood pressure, therefore, people who have diabetes are not suggested using this medicine.

3. Other controlled medicines

Colchicum seed extracts is a traditional medicine for acute gout treatment. In the past, people took it by mistake and had diarrhea and found the uric acid was also decreased. So through medical research, Colchicum seed extracts are used to make uric acid lowering medicine. In case of diarrhea, you should pay more attention to the dosage.


Except for the 3 medicines above, you can also lower the uric acid through health supplements.



ANTI-CRYSTAL Biotech. activates the HPRT and LDH enzyme, to adjust the production of uric acid and improve the uric acid excretion. It can be absorbed in 20 minutes, and lower the uric acid by about 34% in a week. ANTI-CRYSTAL Biotech. is not a medicine, it’s a SGS certified health supplement.